A Microfluidic Platform for Screening and Selection of Monoclonal Antibodies from Single Cells
نویسندگان
چکیده
We report a microfluidic platform for rapid screening and selection of monoclonal antibodies (mAbs) secreted by single cells. The microfluidic platform integrates single-cell handling and compartmentalization, fluorescence detection of antibodies secreted by cells, and cell recovery for reverse transcription polymerase chain reaction (RT-PCR) of antibody genes.
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